WitrynaBrown-like adipocytes can be induced in white fat depots by a different environmental or drug stimuli, known as “browning” or “beiging”. These brite adipocytes express thermogenin UCP1 protein and show different metabolic advantages, such as the ability to acquire a thermogenic phenotype corresponding to standard brown adipocytes that … Witryna15 cze 2011 · Effects of obesity on bone metabolism Abstract. Obesity is traditionally viewed to be beneficial to bone health because of well-established positive effect of...
Assessment of bone metabolism and fracture risk in obese men
WitrynaIntroduction. Osteosarcopenic obesity syndrome (OSO), a complex, whole-body condition related to aging and possibly to some other diseases, impacting body … WitrynaOne of the addressed topics in the current investigation regards the influence of obesity on bone metabolism. Despite of the broadly accepted notion that obesity is … portmeirion woodland walk
Divergent effects of obesity on fragility fractures CIA
Witryna20 gru 2024 · There is a large literature on the relationship between obesity and bone. What we can conclude from this review is that the increase in body weight causes an increase in BMD, both for a mechanical effect and for the greater amount of estrogens present in the adipose tissue. Nevertheless, despite an apparent strengthening of the … WitrynaThe maximum rate of bone mass accumulation is during early adolescence. As such, a focus on optimizing mineral nutrition in school age children, defined here as approximately 5 to 15 years of age, is crucial to minimize the risk of bone loss that occurs later in life leading to osteoporosis and fractures. Optimizing bone mass in this age … WitrynaMetabolic abnormalities, such as diabetes mellitus and obesity, can impact bone quantity and/or bone quality. In this work, we characterize bone material properties, in terms of structure and composition, in a novel rat model with congenic leptin receptor (LepR) deficiency, severe obesity, and hyperglycemia (type 2 diabetes-like condition). portmeiriona christmas storybowls